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Hao Wang, PhD
7+ years of practical microfluidic chip research as a biomedical engineer, as well as research experience in the pathology of STEMI myocardial infarction. Proficient in conducting the physiological study, murine cardiovascular disease models, cell biology studies and microfluidics. Excellent team player and strong builder of prolific collaborations. Good oral and written communication skills accumulated from attending 9+ academic conferences and owing authorship of 16 publications. Easy integration in a multicultural environment with a unique combination of detail-oriented mindset and holistic thinking, distinguished analytical skills, proven ability to meet deadline by working in a fast-paced work environment leading to advancing project.
EDUCATION
Ph.D. in Biomedical Engineering - Oct 2020
Dept. of Biomedical Engineering, USF
Dissertation: "Opto-Fluidic Manipulation of Microparticles and Related Applications"
Master's of Science in Biomedical Engineering - May 2014
Dept. of Biomedical Engineering, USF
Bachelor's Science in Biotechnology – Aug 2011
College of Life Science, ShanDong Normal University
LAB EXPERIENCE
Li Lab, Surgery Department in Morsani Medicine of College, USF. Jan 2022 - Present
Focus: Cardiovascular disease study
Enhanced MIF-modulated signaling cascade regulates metabolic homeostasis to protect aged hearts from I/R insult
High dose Metformin protect aged hearts from acute IR injury
Sestrin2 presents cardiac protection in cardiorenal syndrome 3
Hickman's Group, NanoScience Technology Center, UCF Jan 2021 – Jan 2022
Focus: Multiple-organ-on-a-chip study
Integrate human kidney cells onto multi-organ-on-a-chip (MOOA) system and optimization
Opioid overdose cytotoxicity test on MOOA
Pyayt Lab, Chemical & Biomedical Engineering Department in Engineering College, USF Aug 2016 – Oct 2021
Focus: Apply plasmonic effect in the microfluidic chip
Opto-Fluidic manipulation of microparticles on a chip
Rapid antibody deposition for novel ELISA kit
PUBLICATIONS
Hao Wang, Priyanka Shiveshwarkar, Robert Brzozowski, Arseny Zhdanov, Shulin Shi, Prahathees Eswara, and Anna Pyayt, "Innovative optofluidics and microscopy-based rapid analysis of pathogens," Biomed. Opt. Express 11, 5060-5069 (2020)
Hao Wang, Joseph Tarriela, Priyanka Shiveshwarkar, and Anna Pyayt, "Simulations and experimental demonstration of three different regimes of optofluidic manipulation," Appl. Opt. 60, 593-599 (2021)
Winskas John T., Hao Wang, Arsenii Zhdanov, Surya Cheemalapati, Andrew Deonarine, Sandy Westerheide, and Anna Pyayt. "Different Regimes of Opto-fluidics for Biological Manipulation." Micromachines 10, no. 12 (2019): 802.
Iglesias, Migdalia, Hao Wang, Meredith Krause-Hauch, Di Ren, Linda Ines Zoungrana, Zehui Li, Jie Zhang et al. "Sestrin2 Mediates Metformin Rescued the Age-Related Cardiac Dysfunctions of Cardiorenal Syndrome Type 3." Cells 12, no. 6 (2023): 845.
Zoungrana, Linda Ines, Meredith Krause-Hauch, Hao Wang, Mohammad Kasim Fatmi, Lauryn Bates, Zehui Li, Parth Kulkarni, Di Ren, and Ji Li. "The Interaction of mTOR and Nrf2 in Neurogenesis and Its Implication in Neurodegenerative Diseases." Cells 11, no. 13 (2022): 2048.
Edikan Archibong., Justin Stewart., Hao Wang., Anna Pyayt. “Design of an optofluidic sensor for rapid detection of hemolysis”. Sensors and Actuators B: Chemical, 2019
Cheemalapati S V, John Winskas, Hao Wang, et al. "Subcellular and in-vivo Nano-Endoscopy." Scientific reports 6 (2016): 34400.
Mikhail Ladanov, Surya Cheemalapati, Hao Wang., Yuan Yuan., Piyush Koria., Anna Pyayt. "Plasmono-magetic Material for Precise Photothermal Heating". RSC Advances 8(5), 2660-2666
Archibon Edikan, Tuazon Harry, Hao Wang, Winskas John, Pyayt Anna. "Modular microfluidics: removable microfluidic filters". Journal of Electronic Packaging 138 (4), 041002
Cheemalapati Surya, Heather P. Forth, Hao Wang, Karthik Raj Konnaiyan, Jeffrey M. Morris, and Anna L. Pyayt. "Measurement of thickness of highly inhomogeneous crude oil slicks." Applied Optics 56, no. 11 (2017): E72-E76.
Yoo, J. Y., Dutra, S., Fanfan, D., Sniffen, S., Wang, H., et al. (2020). Comparative analysis of COVID-19 guidelines from six countries: a qualitative study on the US, China, South Korea, the UK, Brazil, and Haiti. BMC public health, 20(1), 1853.
Krause-Hauch, Meredith, Julia Fedorova, Linda Ines Zoungrana, Hao Wang, Mohammad Kasim Fatmi, Zehui Li, Migdalia Iglesias, Lily Slotabec, and Ji Li. "Targeting on Nrf2/Sesn2 Signaling to Rescue Cardiac Dysfunction during High-Fat Diet-Induced Obesity." Cells 11, no. 16 (2022): 2614.
Van Le, Tran Ngoc, Linda Ines Zoungrana, Hao Wang, Mohammad Kasim Fatmi, Di Ren, Meredith Krause-Hauch, and Ji Li. "Sirtuin 1 aggravates hypertrophic heart failure caused by pressure overload via shifting energy metabolism." Biochemical and Biophysical Research Communications (2022).
Fatmi, Mohammad Kasim, Di Ren, Julia Fedorova, Linda Ines Zoungrana, Hao Wang, Kayla Davitt, Zehui Li et al. "Cardiomyocyte Pdk4 response is associated with metabolic maladaptation in aging." Aging Cell (2023): e13800-e13800.
Jovanovic, Alesandra, Bing Xu, Chaoqun Zhu, Di Ren, Hao Wang, Meredith Krause-Hauch, E. Dale Abel, Ji Li, and Yang K. Xiang. "Characterizing Adrenergic Regulation of Glucose Transporter 4-Mediated Glucose Uptake and Metabolism in the Heart." Available at SSRN 4224866.
Li, Zehui, Hao Wang, Linda Ines Zoungrana, Adewale James, Lily Slotabec, Steven Didik, Mohammad Kasim Fatmi, Meredith Krause-Hauch, Edward J. Lesnefsky, and Ji Li. "Administration of metformin rescues age-related vulnerability to ischemic insults through mitochondrial energy metabolism." Biochemical and Biophysical Research Communications 659 (2023): 46-53.
WORK EXPERIENCE
Postdoctoral Scholar | Jan 2022 - Present
Surgery Department in Morsani Medicine of College, University of South Florida
Postdoctoral Scholar | Jan 2021 - 2022
NanoScience Technology Center, University of Central Florida
Research Assistant & Teaching Assistant | Jan 2015 – Dec 2020
Department of Biomedical Engineering, University of South Florida
Academic Translator | Dec 2017
Hospital Administration Training Program, USF Medicine International
Intern Engineer | July 2011 – Sep 2011
Shandong Qilu Monosodium Glutamate Group Co. Ltd, China
RESEARCH SKILLS
Rodent surgery
Cell Culturing
Primary cardiomyocytes isolation and test
Mitochondrial Dynamics Tests
Flow Cytometry
Immunocytochemistry
Spectrophotometry & Microplate Assays
Fabrication of Microfluidic Chip
Cytotoxicity Test
Surface Coating/Treatment
PCR &RNA seq
Immunoblotting
Laser Gear (Class 3) Operation
CONFERENCES AND CONTESTS
SPIE Photonics West 2015, San Francisco (Presenter)
SPIE Optics Photonics 2016, San Diego (Poster Presenter)
National Science Foundation's Innovative Corps (I-Corps) 2016, Washington D.C. (Student Entrepreneur)
Defense Innovation 2017, Tampa (Poster Presenter)
APLU Annual Meeting 2017, Washington D.C. (Poster Presenter)
Building the Case for Health Literacy, National Association of Science 2017, Washington D.C. (Poster Presenter)
Biosensors 2018, Miami (Poster Presenter)
NSF Partnerships for Innovation (PFI) 2018, Washington D.C. (Student Trainee)
AHA Scientific Session 2022, Chicago, Illinois (Moderator Presenter)
LEADERSHIP AND AWARDS
American Heart Association (AHA)member | 2022-Present
President of USF SPIE Student Chapter | 2017-2018
Student Entrepreneur in I-Corps Training Program (NSF) | April-May 2016
SPIE Travel Scholarship | Aug 2015
Second Class Scholarship in college | Sept 2008
Second Prize at National High School Biology Olympic Knowledge Competition | May 2006